Cell Culture Media, Supplements, and Reagents
Medchemexpress LLC Demethoxyencecalin | 19013-07-1 | 99.3% | C13H14O2 | 100 MG
Demethoxyencecalin is a chromene isolated from Helianthus annuus, known for its antifungal activities. It is intended for research use only.
- Exhibits antifungal activities
- Isolated from Helianthus annuus
- For research use only
- Molecular weight of 202.25
- Appears as a yellow to brown liquid
- Store pure form at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Cefetamet (Ro 15-8074) | 65052-63-3 | 99.1% | C14H15N5O5S2 | 50 MG
Cefetamet (Ro 15-8074) is a cephalosporin antibiotic and the active metabolite of Cefetamet pivoxil. It functions by binding to bacterial penicillin-binding protein (PBP), with an IC50 for PBP3 in *Escherichia coli* W3110 of 2.5 μg/mL.
- Demonstrates significant activity against various Gram-negative bacteria (including Enterobacteriaceae, Neisseria species, and Haemophilus influenzae) and Gram-positive bacteria such as Streptococcus.
- Exhibits high in vitro activity against most members of Enterobacteriaceae, Haemophilus influenzae, Neisseria spp., and Streptococcus pneumoniae (MIC90 ≤ 2 μg/mL).
- Kills and lyses Treponema pallidum.
- Can be utilized in research for respiratory tract, urinary tract, ear, nose, and throat infections, and syphilis.
- In vivo studies show it can cure experimental syphilis in rabbits (1-30 mg/kg; i.m.; once).
Medchemexpress LLC Carboxyamidotriazole orotate | 187739-60-2 | 99.7% | 580.76 | 50 MG
Carboxyamidotriazole Orotate is an orally bioavailable signal transduction inhibitor. It acts as a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways, demonstrating anti-tumor, anti-inflammatory, and antiangiogenic effects.
- Inhibits cell proliferation in specific leukemia cell lines.
- Reduces phosphorylation of Bcr-Abl kinase targets.
- Induces a 50% growth reduction in chronic myelogenous leukemia (CML) cell lines.
- Demonstrates dose-dependent inhibition of Bcr-Abl levels.
- Exhibits antitumor activity in CML xenografts, leading to increased survival.
- Has been evaluated in multiple clinical trials for various cancers.
- Intended for research use only.
Medchemexpress LLC Brilacidin tetrahydrochloride | 1224095-99-1 | 99.1% | 1082.75 | 50 MG
Brilacidin tetrahydrochloride | 1224095-99-1 | 99.1% | 1082.75 | 50 MG
Medchemexpress LLC RTI-7470-44 (hTAAR1 Antagonist) | 825658-63-7 | 99.9% | 449.84 | 50 MG
RTI-7470-44 is a potent, selective, and blood-brain barrier (BBB) penetrant human trace amine-associated receptor subtype 1 (hTAAR1) antagonist. It exhibits moderate metabolic stability and a favorable preliminary off-target profile, capable of increasing the spontaneous firing rate of mouse ventral tegmental area (VTA) dopaminergic neurons. It can be utilized for research into schizophrenia, agent addiction, and Parkinson's disease (PD).
- Potent, selective, and BBB penetrant hTAAR1 antagonist
- IC50 value of 8.4 nM and Ki value of 0.3 nM for human TAAR1
- Moderate metabolic stability
- Favorable preliminary off-target profile
- Increases spontaneous firing rate of VTA dopaminergic neurons
- Suitable for research into schizophrenia, agent addiction, and Parkinson's disease
Medchemexpress LLC Roxithromycin (Standard) | 80214-83-1 | 98.2% | 50 MG
Roxithromycin (Standard), also known as RU-28965 (Standard), is an analytical standard for Roxithromycin. This product is designed for research and analytical applications. Roxithromycin (RU-28965) itself is a semi-synthetic macrolide antibiotic. As an analytical standard, it serves as a reference standard for assays and is frequently utilized in qualitative, quantitative, and methodological research experiments, including techniques such as HPLC, GC, and MS.
- Analytical standard for roxithromycin
- Intended for research and analytical applications
- Serves as a reference standard for assays
- Utilized in qualitative, quantitative, and methodological research experiments
- Suitable for techniques such as HPLC, GC, and MS
Medchemexpress LLC Lexithromycin | 53066-26-5 | MFCD00864895 | 97.6% | 762.97 g/mol | C38H70N2O13 | 10 MG
Lexithromycin (erythromycin A 9-methoxime) is a semi-synthetic derivative of erythromycin A with antibacterial activity. It is supplied as a characterized research chemical for in vitro and pharmaceutical research, with documented analytical data and available small pack sizes for laboratory use.
- Semi-synthetic erythromycin derivative with antibacterial activity.
- Suitable for in vitro and pharmaceutical research applications.
- Documented purity determined by RP-HPLC (97.6%).
- Molecular weight 762.97 g/mol and formula C38H70N2O13.
- Provided in small pack sizes for convenient laboratory use.
Medchemexpress LLC Xanomeline | 131986-45-3 | MFCD00867179 | 99.95% | 281.42 g·mol⁻¹ | C14H23N3OS | 10 MG
Xanomeline is a selective muscarinic M1/M4 receptor agonist used as a research reagent in neuroscience to investigate cholinergic signaling and neuropsychiatric disorders. It is provided as a high-purity chemical for laboratory use; consult the product data sheet and safety data sheet for handling, storage, and experimental guidance.
- Selective muscarinic M1/M4 receptor agonist.
- High purity suitable for analytical and biological research.
- Available in multiple small-scale quantities for laboratory use.
- Supplied with a product data sheet and a safety data sheet.
- Used to study cholinergic signaling and neuropsychiatric disease models.
- Compatible with in vitro and in vivo experimental protocols.
Medchemexpress LLC Jak2 inhibitor v | 195371-52-9 | MFCD00023550 | 96.9% | 344.45 | C23H24N2O | 10 MG
NSC 42834 (JAK2 Inhibitor V) is a research-grade small-molecule inhibitor of Janus kinase 2 (JAK2). It inhibits autophosphorylation of wild-type JAK2 and the V617F mutant and is used in cellular and biochemical studies of JAK/STAT signaling and oncology-related research. The compound is supplied as a characterized solid with supporting analytical documentation.
- Small-molecule JAK2 inhibitor active against JAK2-WT and JAK2-V617F.
- Documented purity and analytical data provided.
- Suitable for in vitro and preclinical research on JAK/STAT signaling.
- Provided with datasheet, certificate of analysis, and safety data sheet.
- Molecular weight 344.45 g/mol and formula C23H24N2O.
Medchemexpress LLC Rab1b protein, human (HEK293, Fc tag) | 97.9% | 100 UG
Recombinant human RAB1B protein expressed in HEK293 cells and produced as an Fc fusion. Supplied as a purified research-grade protein in microgram quantities for use in biochemical assays, binding studies, and antibody validation. Store and handle according to the supplier datasheet.
Medchemexpress LLC Xanomeline 25mg | 131986-45-3 | 25MG
Xanomeline as an effective and selective muscarinic type 1 and type 4 (M1/M4) receptor agonist increases neuronal excitability Xanomeline can be used for the research of neurological disorders such as schizophrenia[1 [2